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Early worsening of anxiety, agitation and irritability are thought to be common among people commencing antidepressants, especially for anxiety disorders. Sequential drug treatment algorithm for agitation and aggression in Alzheimer’s and mixed dementia. Effect of Citalopram on Emotion Processing in Humans: A Combined 5-HT1A [11C]CUMI-101 PET and Functional MRI Study. The effect of jitteriness/anxiety syndrome on suicide rates has not been evaluated. It appears to be a separate syndrome from akathisia, but evidence for this assertion was limited. This study was not commissioned, funded or sponsored by any pharmaceutical company or other financial enterprise. Sequential drug treatment algorithm for agitation and aggression in Alzheimer’s and mixed dementia. Effect of Citalopram on Emotion Processing in Humans: A Combined 5-HT1A [11C]CUMI-101 PET and Functional MRI Study. Panic-like escape response elicited in mice by exposure to CO 2 , but not hypoxia.
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Of 245 articles identified, 107 articles were included for review.
To review systematically all evidence relating to jitteriness/ anxiety syndrome to identify: constituent symptoms; medications implicated; disorders in which it was reported; incidence; time course; management strategies; relationship of this syndrome to therapeutic response; distinction between syndrome and akathisia; relationship between syndrome and suicide; and genetic predispositions.